CARLA – Computer Vision Approaches in Low Annotation Regimes: biomedical and facial image analysis (2022-2025)

The CARLA project — “Métodos de visión artificial en entornos de pocas anotaciones: análisis de imagen biomédica y facial” — focuses on the development of AI methods for visual recognition in low-data environments, where annotated datasets are scarce or expensive to obtain.
Led by the Computer Vision and Pattern Discovery (CVPD) group at the University of the Basque Country (UPV/EHU), CARLA targets two key application domains:
- Biomedical image analysis: Enhancing diagnostic tools and research through robust AI-based segmentation and classification under minimal annotation constraints.
- Facial image analysis: Improving recognition and aesthetics assessment tasks with annotation-efficient deep learning techniques.
🔬 Scientific Goals
The CARLA project focuses on the development of advanced computer vision and machine learning techniques to address two core challenges:
- The need for large amounts of annotated data for training state-of-the-art models.
- The limited generalization capacity of these models when applied to new but related domains.
Its specific goals are:
Develop deep learning techniques capable of operating in low-annotation settings by leveraging data characteristics, feature representations, and task-specific regularization strategies.
Explore domain adaptation and domain generalization approaches to improve the transferability of models across different but related visual domains (e.g., from one biomedical imaging modality to another).
Integrate and validate these techniques on two application areas:
- Biomedical image analysis, focusing on segmentation and classification tasks.
- Facial image analysis, particularly on face interpretation and aesthetic evaluation.
Deliver tools and pipelines that can be integrated into open-source frameworks, promoting reproducibility, usability, and transfer of methods to real-world scenarios.
The project combines theoretical research with practical experimentation using both synthetic datasets and real annotated collections in the biomedical and facial imaging domains.
👥 Project Team
Principal Investigators:
- Dr. Fadi Dornaika (Ikerbasque Research Professor, UPV/EHU)
- Dr. Ignacio Arganda-Carreras (Ikerbasque Research Associate Professor, UPV/EHU, DIPC, Biofisika Institute)
Research Team:
- Dr. Nagore Barrena (Assistant Professor, UPV/EHU)
- Dr. Urtzi Ayesta (Ikerbasque Research Professor, UPV/EHU)
Work Team:
- Dr. Fares Bougourzi (Researcher, University of Salento, Italy)
- Dr. Alireza Bosaghzadeh (Associate Professor, Shahid Rajaee Teacher Training University, Iran)
- Dr. Donglai Wei (Associate Professor, Boston College, USA)
- Daniel Franco-Barranco (PhD student, Donostia International Physics Center)
🕒 Timeline
- Start: September, 1 2022
- End: August, 31 2025
💰 Funding
- Funded by the Spanish Ministry of Science and Innovation (MCIN) under the Generación de Conocimiento 2021 (Proyectos de Investigación Orientada) program.
- Total funding: 101,640€ (including indirect costs)
- Reference code: PID2022-137580OB-I00

Ignacio Arganda-Carreras
Ikerbasque Research Associate Professor
My research interests include image processing, computer vision, and deep learning for biomedical applications.
Fadi Dornaika
Ikerbasque Research Professor
Ikerbasque Research Professor with expertise in computer vision, machine learning, and pattern recognition.
Nagore Barrena
Assistant Professor
My research focuses on computer vision and deep learning, with applications to biomedical and natural images.
Daniel Franco-Barranco
Postdoctoral Researcher
My primary focus is on the development of deep learning solutions for the segmentation of organelles in large-scale and multimodal electron microscopy images.
Lenka Backová
PhD Student
My research focuses on deep learning-based bioimage analysis and biophysical modeling of multicellular systems.
Aitor González-Marfil
PhD Student
My research focuses on generalizable deep learning methods for computer vision.
Sally El Hajjar
Former PhD Student
Former PhD student at CVPD, now Senior Research Fellow at The New School (NYC), working on climate risk prediction using deep learning.
Bouthaina Slika
Former PhD Student
My research focuses on generalizable deep learning methods for computer vision for medical image analysis.
Mohamad Abou Ali
Postdoctoral Researcher
I develop generalizable deep learning methods for biomedical imaging, advancing diagnostic accuracy, data augmentation, and intelligent healthcare systems.
Francisco Javier Iriarte
PhD Student
I am currently focusing my research in Explainable AI for model monitoring applications.
Xabier Lekunberri
PhD Student
The primary focus of my research is to improve fisheries management through computer vision.
Pendar Alirezazadeh
Postdoctoral Research Fellow
Postdoctoral researcher specializing in Edge AI, deep learning quantization, and efficient neural network models for embedded systems.
Danyang Sun
Lecturer & Postdoctoral Researcher
Developing data augmentation and feature extraction solutions in medical-engineering convergence to enhance the clinical utility of AI-assisted therapy.
Jingjun Bi
Former PhD student
I am interested in imbalanced learning, multi-view learning, graph convolutional neural networks, and classification.
Zoulfikar Ibrahim
Professor and Software Engineer
I develop scalable graph-based machine learning methods and teach cutting-edge technologies in web and software development. My focus spans semi-supervised learning, data analysis, and full-stack engineering.
Gaby Maroun
PhD Student
My research focuses on generalizable deep learning methods for computer vision, with applications in segmentation, classification, and visual understanding.
Salah Eddine Bekhouche
Former PhD Student
My research focuses on applied computer vision, pattern recognition, machine learning, and deep learning with a deep interest in biometrics, facial analysis, document understanding, and image/video generation.











